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Ozempic Injections in Riyadh are also a prescription drug whose recent years of active existence have brought it rather strong popularity because of its two-pronged usage in the therapy of type 2 diabetes and weight loss. Ozempic, manufactured by Novo Nordisk, is an injectable drug that is used once a week, and it is a drug of GLP-1 receptor agonist. It has started to gain popular demand not only among diabetic controls but also among others who want to find medical aid in their weight control, which has elicited common concern and debate among the health community.
What is Ozempic?
Ozempic is mainly used in the management of type 2 diabetes in adults with the aim of better blood sugar levels, complemented with diet and physical activity. It replicates the effect of a natural hormone known as glucagon-like peptide-1 (GLP-1) that is secreted into the intestine when one eats. GLP-1 is vital in balancing the level of sugar in the blood by increasing production of insulin, restraining discharge of glucagon, and retarding evolution of stomach. These activities curb high blood sugar and appetite for a full-stomach feeling.
As an active ingredient of Ozempic, semaglutide is a long-acting GLP-1 receptor stimulant, and in-between injections occur only once per week. It is administered through a pre-filled injection pen, and its users normally administer it subcutaneously through the abdomen, the thigh, or the arm.
Medical Uses of Ozempic
Management of Type 2 diabetes
Ozempic is one solution for adults who have a type 2 diabetes problem in reducing their blood sugar content, whereby healthy lifestyle choices like eating and exercising are insufficient. Clinical trials have proven that Ozempic has a strong influence on HbA1c lowering (a long-term measurement of blood sugar control) and could also contribute to the reduction of major cardiovascular incidents like heart attacks and strokes among patients with previously diagnosed heart illnesses.
Off-label use (Weight Management)
Although the FDA has not approved Ozempic as a weight loss drug, people have turned to it more and more to lose weight. It is an off-label prescription that is recommended by various clinicians to obese individuals and overweight patients who have complications caused by their weight. Clinical trial results indicate that semaglutide causes significant weight loss, particularly in combination with diet and exercise. Because of its efficacy, a larger dose of semaglutide, marketed as Wegovy, has been approved by the FDA for use specifically in chronic weight management.
Mechanism of action of Ozempic
Ozempic works in several mechanisms:
- releases insulin in case of increased blood glucose.
- Inhibits the release of glucagon, which minimizes the release of glucose in the liver.
- Reduces gastric emptying, a process that delays digestion, resulting in satiety (feeling full).
- Contributes to a decreased appetite and thus control of calories.
- All these effects make Ozempic very effective in not only blood sugar but also weight loss.
Dosage and Administration
The initiation of Ozempic may begin with a dose of 0.25 mg once at least once every week to reduce gastrointestinal reactions before subsequent elevation of dose to 0.5 mg and possibly 2.0 mg weekly, depending on tolerance and treatment intentions. One should adhere to the prescription of a health worker and should not regulate the dosage independently.
The injection may be administered at any time of the day, irrespective of meals, and administered on the same day every week. The users should change the injection sites after every use to avoid irritation on the skin.
Side Effects
Ozempic is like all other medicines in that it may come with side effects, some of which do not afflict everybody. Side effects, mostly common, are:
- Nausea
- Vomiting
- Diarrhea
- Constipation
- Abdominal pain
These gastric complaints will stop after some time since the body learns to get used to the medication. Yet, there are severe side effects, which, however, are rare:
- Inflammation of the pancreas or pancreatitis.
- Gallbladder disease
- Kidney problems
- Allergic reactions
- Tumors of the thyroid gland (animals- causing a boxed warning)
Ozempic should not be used by patients with a history of multiple endocrine neoplasia syndrome type 2 or medullary thyroid carcinoma history (in the patient and family).
Contraindications and Precautions
Ozempic cannot be used by individuals with type 1 diabetes or diabetic ketoacidosis. Again, it must not be taken when pregnant or nursing a baby without consulting a doctor. Patients who have a history of pancreatitis or gastrointestinal diseases should be taken with caution.
Given that Ozempic delays digestion, it is likely to interfere with the absorption of the drug taken by mouth. Patients need to disclose every drug they use to their doctors to avoid any interactions.
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